Tucidinostat (Chidamide)
Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
| Trivial name | HBI-8000, CS-055 |
| Catalog Number | S8567 |
| Molecular Formula | C22H19FN4O2 |
| CAS# | 1616493-44-7 |
| Inchi | InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)/b10-5+ |
| Inchi Key | WXHHICFWKXDFOW-BJMVGYQFSA-N |
| SMILES | C1=CC(=CN=C1)C=CC(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=C(C=C3)F)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/tucidinostat-chidamide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/tucidinostat-chidamide-chemical-structure-s8567.gif |