Pemrametostat (GSK3326595)

Pemrametostat (GSK3326595, EPZ015938) is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) and potently inhibits tumor growth in vitro and in vivo in animal models.

Trivial name EPZ015938
Catalog Number S8664
Molecular Formula C24H32N6O3
CAS# 1616392-22-3
Inchi InChI=1S/C24H32N6O3/c1-17(31)30-10-7-20(8-11-30)28-23-12-22(26-16-27-23)24(33)25-13-21(32)15-29-9-6-18-4-2-3-5-19(18)14-29/h2-5,12,16,20-21,32H,6-11,13-15H2,1H3,(H,25,33)(H,26,27,28)/t21-/m0/s1
Inchi Key JLCCNYVTIWRPIZ-NRFANRHFSA-N
SMILES CC(=O)N1CCC(CC1)NC2=NC=NC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O
Size 1g
Supplier Page http://www.selleckchem.com/products/gsk3326595-epz015938.html
Additional Information https://file.selleck.cn/downloads/struct/gsk3326595-chemical-structure-epz015938-S8664.gif