Pemrametostat (GSK3326595)
Pemrametostat (GSK3326595, EPZ015938) is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) and potently inhibits tumor growth in vitro and in vivo in animal models.
Trivial name | EPZ015938 |
Catalog Number | S8664 |
Molecular Formula | C24H32N6O3 |
CAS# | 1616392-22-3 |
Inchi | InChI=1S/C24H32N6O3/c1-17(31)30-10-7-20(8-11-30)28-23-12-22(26-16-27-23)24(33)25-13-21(32)15-29-9-6-18-4-2-3-5-19(18)14-29/h2-5,12,16,20-21,32H,6-11,13-15H2,1H3,(H,25,33)(H,26,27,28)/t21-/m0/s1 |
Inchi Key | JLCCNYVTIWRPIZ-NRFANRHFSA-N |
SMILES | CC(=O)N1CCC(CC1)NC2=NC=NC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/gsk3326595-epz015938.html |
Additional Information | https://file.selleck.cn/downloads/struct/gsk3326595-chemical-structure-epz015938-S8664.gif |