GSK591
GSK591 (EPZ015866, GSK3203591) is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 4 nM.
| Trivial name | EPZ015866, GSK3203591 |
| Catalog Number | S8111 |
| Molecular Formula | C22H28N4O2 |
| CAS# | 1616391-87-7 |
| Inchi | InChI=1S/C22H28N4O2/c27-20(15-26-11-9-16-4-1-2-5-18(16)14-26)13-24-22(28)17-8-10-23-21(12-17)25-19-6-3-7-19/h1-2,4-5,8,10,12,19-20,27H,3,6-7,9,11,13-15H2,(H,23,25)(H,24,28)/t20-/m0/s1 |
| Inchi Key | TWKYXZSXXXKKJU-FQEVSTJZSA-N |
| SMILES | C1CC(C1)NC2=NC=CC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/gsk591-epz015866-gsk3203591.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk591-epz015866-gsk3203591-chemical-structure-s8111.gif |