EPZ015666 (GSK3235025)
EPZ015666 (GSK3235025) is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.
| Catalog Number | S7748 |
| Molecular Formula | C20H25N5O3 |
| CAS# | 1616391-65-1 |
| Inchi | InChI=1S/C20H25N5O3/c26-17(10-25-6-5-14-3-1-2-4-15(14)9-25)8-21-20(27)18-7-19(23-13-22-18)24-16-11-28-12-16/h1-4,7,13,16-17,26H,5-6,8-12H2,(H,21,27)(H,22,23,24)/t17-/m0/s1 |
| Inchi Key | ZKXZLIFRWWKZRY-KRWDZBQOSA-N |
| SMILES | C1CN(CC2=CC=CC=C21)CC(CNC(=O)C3=CC(=NC=N3)NC4COC4)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/epz015666.html |
| Additional Information | https://file.selleck.cn/downloads/struct/epz015666-chemical-structure-s7748.gif |