MEN1703(SEL24,SEL24-B489)
MEN1703(SEL24-B489,SEL24, Pim/flt3 kinase inhibitor SEL24) is a potent, type I, orally active, dual inhibitor of PIM and FLT3-ITD, that exhibits Kd values of 2 nM for PIM1, 2 nM for PIM2 and 3 nM for PIM3, respectively. MEN1703 exhibits its broad therapeutic potential in treatment of acute myeloid leukemia.
| Trivial name | SEL24, Pim/flt3 kinase inhibitor SEL24 |
| Catalog Number | E4598 |
| Molecular Formula | C20H13N3O2 |
| CAS# | 1616359-00-2 |
| SMILES | C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/men1703.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4598-MEN1703-SEL24-SEL24-B489-chemical-structure.png |