SGC-CBP30
SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively. Exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4(1)) and BRD4(2) respectively.
| Trivial name | N/A |
| Catalog Number | S7256 |
| Molecular Formula | C28H33ClN4O3 |
| CAS# | 1613695-14-9 |
| Inchi | InChI=1S/C28H33ClN4O3/c1-18(32-11-13-35-14-12-32)17-33-25-8-7-22(28-19(2)31-36-20(28)3)16-24(25)30-27(33)10-6-21-5-9-26(34-4)23(29)15-21/h5,7-9,15-16,18H,6,10-14,17H2,1-4H3/t18-/m0/s1 |
| Inchi Key | GEPYBHCJBORHCE-SFHVURJKSA-N |
| SMILES | CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC(=C(C=C4)OC)Cl)CC(C)N5CCOCC5 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/sgc-cbp30.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SGC-CBP30-chemical-structure-s7256.gif |