VX-803 (M4344)

VX-803 (M4344, ATR inhibitor 2) is an ATP-competitive, orally active, and selective inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase with Ki of < 150 pM. VX-803 (M4344) potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with IC50 of 8 nM. VX-803 (M4344) exhibits potential antineoplastic activity.

Price Not Available 100mg VX-803 (M4344) Supplier Page

Trivial name	ATR inhibitor 2
Catalog Number	S9639
Molecular Formula	C25H29F2N9O3
CAS#	1613191-99-3
SMILES	C1CN(CCC1C(=O)N2CCN(CC2)C3COC3)C4=C(C=NC=C4NC(=O)C5=C6N=CC(=CN6N=C5N)F)F
Size	100mg
Supplier Page	http://www.selleckchem.com/products/vx803-m4344.html
Additional Information	https://file.selleck.cn/downloads/struct/s9639-vx-803-m4344-chemical-structure.gif