Unesbulin (PTC596)
Unesbulin (PTC596) is a second-generation BMI-1 inhibitor that accelerates BMI-1 degradation. PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis. IC50 values at 72 hours ranged from 68 to 340 nM in mantle cell lymphoma (MCL) cell lines.
| Trivial name | N/A |
| Catalog Number | S8820 |
| CAS# | 1610964-64-1 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ptc596.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ptc596-chemical-structure-s8820.gif |