Amredobresib
Amredobresib (BI894999) is an oral inhibitor of BET, which acts as an acetyl-lysine mimic. It prevents the bromodomains BRD4-BD1 and BRD4-BD2 from binding to acetylated histones, with an IC50 of 5 nM for BRD4-BD1 and 41 nM for BRD4-BD2.
| Trivial name | BI894999 |
| Catalog Number | E4609 |
| Molecular Formula | C22H16N2O2 |
| CAS# | 1610044-98-8 |
| SMILES | CC1=CC2=NC(=C(N2C=C1)C(=O)C(=O)C3=CC=CC=C3)C4=CC=CC=C4 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/amredobresib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4609-Amredobresib-chemical-structure.png |