HA15
HA15 is a molecule that targets specifically HSPA5 (Heat shock 70kDa protein 5) also known as BiP (Immunoglobulin heavy-chain-binding protein) or Grp78 (glucose-regulated protein 78). HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
| Trivial name | N/A |
| Catalog Number | S8299 |
| Molecular Formula | C23H22N4O3S2 |
| CAS# | 1609402-14-3 |
| Inchi | InChI=1S/C23H22N4O3S2/c1-15(28)24-23-25-20(14-31-23)16-7-4-8-17(13-16)26-32(29,30)22-12-6-9-18-19(22)10-5-11-21(18)27(2)3/h4-14,26H,1-3H3,(H,24,25,28) |
| Inchi Key | LBSMEKVVMYSTIH-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=NC(=CS1)C2=CC(=CC=C2)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/ha15.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ha15-chemical-structure-s8299.gif |