Indirubin-3′-monoxime
Indirubin-3′-monoxime (Indirubin-3′-oxime) is a selective CDK inhibitor with IC50 of 0.18 μM, 0.44 μM, 0.25 μM, 3.33 μM, 0.065 μM for CDK1-cyclinB, CDK2-cyclinA, CDK2-cyclinE, CDK4-cyclinD1, CDK5-p35,respectively. Indirubin-3′-monoxime is a direct and selective 5-lipoxygenase inhibitor with IC50 of 7.8-10 µM.
Trivial name | Indirubin-3'-oxime |
Catalog Number | S2009 |
Molecular Formula | C16H11N3O2 |
CAS# | 160807-49-8 |
Inchi | InChI=1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17,21H,(H,18,20)/b15-13+,19-14+ |
Inchi Key | HBDSHCUSXQATPO-OIXOFKMYSA-N |
SMILES | C1=CC=C2C(=C1)C(=C(N2)O)C3=C(C4=CC=CC=C4N3)N=O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/indirubin-3-monoxime.html |
Additional Information | https://file.selleck.cn/downloads/struct/indirubin-3-monoxime-chemical-structure-s2009.gif |