Sodium stibogluconate
Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1) activity at 10 μg/ml and similar degrees of inhibition of SHP-2 and PTP1B requires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.
Trivial name | SSG, Stibogluconate sodium, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001 |
Catalog Number | S2435 |
Molecular Formula | C12H35Na3O26Sb2 |
CAS# | 16037-91-5 |
SMILES | O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].OCC(O)C1O[Sb]2(O)(OC1C(O2)C([O-])=O)O[Sb]34([O-])OC(C(O)CO)C(O3)C(O4)C([O-])=O |
Size | 200mg |
Supplier Page | http://www.selleckchem.com/products/sodium-stibogluconate.html |
Additional Information | https://file.selleck.cn/downloads/struct/stibogluconate-sodium-chemical-structure-s2435.gif |