GSK-843
GSK-843 (GSK’843) is a selective inhibitor of receptor-interacting protein kinase 3 (RIP3 or RIPK3) that binds to the RIP3 kinase domain with an IC50 of 8.6 nM and effectively inhibits its enzymatic activity with an IC50 of 6.5 nM.
| Trivial name | GSK'843 |
| Catalog Number | S3443 |
| Molecular Formula | C20H23N3O3 |
| CAS# | 1601496-05-2 |
| Inchi | InChI=1S/C20H23N3O3/c1-22(2)11-17-18(25-4)8-13(9-19(17)26-5)16-12-23(3)20(24)15-10-21-7-6-14(15)16/h6-10,12H,11H2,1-5H3 |
| Inchi Key | RBUYFHLQNPJMQM-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)C)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gsk-843.html |
| Additional Information | https://file.selleck.cn/downloads/struct/S3443-GSK-843-chemical-structure.png |