Tilfrinib
Tilfrinib (Compound 4f) is a potent and selective inhibitor of the tyrosine-protein kinase Brk/PTK6, with an IC50 of 3.15 nM. It demonstrates significant anti-proliferative activity against breast cancer cell lines MCF7, HS-578T, and BT-549.
Catalog Number | E4658 |
Molecular Formula | C24H28N8O2 |
CAS# | 1600515-49-8 |
SMILES | C1CN(CCC1CC#N)C2=NC3=C(C(=O)NN=C3)C(=N2)NC4=CC=C(C=C4)N5CCC(CC5)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/tilfrinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4658-Tilfrinib-chemical-structure.png |