(E/Z)-BCI

(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.

Price Not Available 10mM/1mL (E/Z)-BCI Supplier Page
Trivial name BCI, NSC 150117
Catalog Number S0056
Molecular Formula C22H23NO
CAS# 15982-84-0
SMILES C1CCC(CC1)NC2C3=CC=CC=C3C(=O)C2=CC4=CC=CC=C4
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/dual-specificity-protein-phosphatase-1-6-Inhibitor-bcl.html
Additional Information https://file.selleck.cn/downloads/struct/s0056-dual-specificity-protein-phosphatase-1-6-inhibitor-chemical-structure.gif