ISRIB (trans-isomer)
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.
| Trivial name | N/A |
| Catalog Number | S7400 |
| Molecular Formula | C22H24Cl2N2O4 |
| CAS# | 1597403-47-8 |
| Inchi | InChI=1S/C22H24Cl2N2O4/c23-15-1-9-19(10-2-15)29-13-21(27)25-17-5-7-18(8-6-17)26-22(28)14-30-20-11-3-16(24)4-12-20/h1-4,9-12,17-18H,5-8,13-14H2,(H,25,27)(H,26,28)/t17-,18- |
| Inchi Key | HJGMCDHQPXTGAV-IYARVYRRSA-N |
| SMILES | C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/isrib-trans-isomer.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ISRIB(trans-isomer)-chemical-structure-s7400.gif |