AZ191
AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM in a cell-free assay, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.
Trivial name | N/A |
Catalog Number | S7338 |
Molecular Formula | C24H27N7O |
CAS# | 1594092-37-1 |
Inchi | InChI=1S/C24H27N7O/c1-29-10-12-31(13-11-29)17-4-5-21(23(14-17)32-3)28-24-26-9-7-20(27-24)19-16-30(2)22-15-25-8-6-18(19)22/h4-9,14-16H,10-13H2,1-3H3,(H,26,27,28) |
Inchi Key | ZYVXTMKTGDARKR-UHFFFAOYSA-N |
SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/az191.html |
Additional Information | https://file.selleck.cn/downloads/struct/AZ191-chemical-structure-s7338.gif |