kira6
kira6 is a potent type II IRE1α kinase inhibitor with an IC50 of 0.6 μM. It dose-dependently inhibits IRE1α(WT) kinase activity, XBP1 RNA cleavage, Ins2 RNA cleavage and oligomerization.
| Trivial name | N/A |
| Catalog Number | S8658 |
| Molecular Formula | C28H25F3N6O |
| CAS# | 1589527-65-0 |
| Inchi | InChI=1S/C28H25F3N6O/c1-27(2,3)25-36-22(23-24(32)33-13-14-37(23)25)20-11-12-21(19-10-5-4-9-18(19)20)35-26(38)34-17-8-6-7-16(15-17)28(29,30)31/h4-15H,1-3H3,(H2,32,33)(H2,34,35,38) |
| Inchi Key | NOHQEAFAESMMDX-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=NC(=C2N1C=CN=C2N)C3=CC=C(C4=CC=CC=C43)NC(=O)NC5=CC=CC(=C5)C(F)(F)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/kira6.html |
| Additional Information | https://file.selleck.cn/downloads/struct/kira6-chemical-structure-s8658.gif |