Rupatadine
Rupatadine (UR-12592) is a potent, orally active and long-lasting dual antagonist of platelet-activating factor (PAF) and histamine (H1) with Ki of 0.55 μM and 0.1 μM, respectively. It exhibits anti-fibrosis effect and can be used in research on treatments for pulmonary fibrosis, allergic and inflammatory conditions involving both platelet-activating factor (PAF) and histamine.
| Catalog Number | E7255 |
| Molecular Formula | C50H46CaF2N2O8 |
| CAS# | 158876-82-5 |
| Inchi | InChI=1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/t2*18-,19-;/m11 ./s1 |
| Inchi Key | RHGYHLPFVJEAOC-ZGSPBYFDSA-L |
| SMILES | C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.[Ca+2] |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/rupatadine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7255-Rupatadine-chemical-structure.png |