Licofelone (ML3000)
Licofelone (ML3000, Compound 3e) is a dual inhibitor of COX and 5-lipoxygenase (5-LOX) with IC50 of 0.21 μM and 0.18 μM, respectively. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Licofelone is considered as a treatment for osteoarthritis.
| Trivial name | N/A |
| Catalog Number | S2121 |
| Molecular Formula | C23H22ClNO2 |
| CAS# | 156897-06-2 |
| SMILES | CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/licofelone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Licofelone-chemical-structure-s2121.gif |