Rostafuroxin
Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na+,K+-ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus (RSV)-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity.
| Trivial name | PST 2238 |
| Catalog Number | E7922 |
| Molecular Formula | C19H26O3 |
| CAS# | 156722-18-8 |
| Inchi | InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1 |
| Inchi Key | OSVMTWJCGUFAOD-KZQROQTASA-N |
| SMILES | CC12CCC(=O)C(=C1CCC3C2CCC4(C3CCC4=O)C)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/rostafuroxin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7922-rostafuroxin-chemical-structure-tube.png |