Alvimopan
Alvimopan (LY 246736, ADL 8-2698) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.
| Trivial name | LY 246736, ADL 8-2698 |
| Catalog Number | S5935 |
| Molecular Formula | C25H32N2O4 |
| CAS# | 156053-89-3 |
| Inchi | InChI=1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1 |
| Inchi Key | UPNUIXSCZBYVBB-JVFUWBCBSA-N |
| SMILES | CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/alvimopan.html |
| Additional Information | https://file.selleck.cn/downloads/struct/alvimopan-chemical-structure-s5935.gif |