Rosiglitazone maleate
Rosiglitazone maleate, a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.
Trivial name | BRL-49653C, BRL-49653 |
Catalog Number | S2505 |
Molecular Formula | C18H19N3O3S.C4H4O4 |
CAS# | 155141-29-0 |
Inchi | InChI=1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1- |
Inchi Key | SUFUKZSWUHZXAV-BTJKTKAUSA-N |
SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Rosiglitazone-maleate.html |
Additional Information | https://file.selleck.cn/downloads/struct/Rosiglitazone-maleate-chemical-structure-S2505.gif |