Stauprimide
A cell-permeable analog of Staurosporine that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.
Catalog Number | ABS-065 |
Alternative Name(s) | N-Benzoyl-7-oxostaurosporine |
CAS# | 154589-96-5 |
Inchi | InChI=1S/C35H28N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16,23-24,31H,17H2,1-3H3,(H,36,40,41)/t23-,24-,31-,35+/m1/s1 |
Inchi Key | MQCCJEYZKWZQHU-MPRCCEKMSA-N |
SMILES | CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(=O)NC6=O)N(C)C(=O)C9=CC=CC=C9)OC |
Size | Inquiry |
Supplier Page | https://www.agingclocks.com/stauprimide-item-1529.html |