NU7026
NU7026 (LY293646) is a potent DNA-PK inhibitor with IC50 of 0.23 μM in cell-free assays, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR. NU7026 enhances G2/M cell arrest and apoptosis.
| Trivial name | LY293646 |
| Catalog Number | S2893 |
| Molecular Formula | C21H18F2N2O2 |
| CAS# | 154447-35-5 |
| Inchi | InChI=1S/C21H18F2N2O2/c22-19-11-15(12-20(23)21(19)26)18-13-24-6-5-17(18)14-1-3-16(4-2-14)25-7-9-27-10-8-25/h1-6,11-13,26H,7-10H2 |
| Inchi Key | YUYJEQHNWKQNBT-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=CC=C(C=C2)C3=C(C=NC=C3)C4=CC(=C(C(=C4)F)O)F |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/nu7026.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NU7026-chemical-structure-s2893.gif |