Thioguanine
Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn’s disease, rheumatoid arthritis) and organ transplant recipients.
| Trivial name | NSC 752, 6-Thioguanine, 2-Amino-6-purinethiol |
| Catalog Number | S1774 |
| Molecular Formula | C5H5N5S |
| CAS# | 154-42-7 |
| Inchi | InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11) |
| Inchi Key | WYWHKKSPHMUBEB-UHFFFAOYSA-N |
| SMILES | C1=NC2=C(N1)C(=S)N=C(N2)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Thioguanine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Thioguanine-chemical-structure-S1774.gif |