AG-1478
AG-1478 is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase IIIα (PI4KA).
| Trivial name | Tyrphostin AG-1478, NSC 693255 |
| Catalog Number | S2728 |
| Molecular Formula | C18H12N4OS |
| CAS# | 153436-53-4,175178-82-2 |
| Inchi | InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24) |
| Inchi Key | GSRTWXVBHGOUBU-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ag-1478-tyrphostin-ag-1478.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ag-1478-tyrphostin-ag-1478-chemical-structure-s2728.gif |