BMS 182874
BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.
| Catalog Number | T26841 |
| Alternative Name(s) | BMS182874 , BMS-182874 |
| Research Area | GPCR/G Protein |
| Molecular Formula | C17H19N3O3S |
| CAS# | 153042-42-3 |
| Purity | 98.38% |
| SMILES | O=S(=O)(NC=1ON=C(C1C)C)C2=CC=CC=3C2=CC=CC3N(C)C |
| Size | 25 mg |
| Supplier Page | https://www.targetmol.com/compound/BMS 182874 |
| Additional Information | https://www.targetmol.com/datasheet/T26841 |