Adezmapimod (SB203580)
Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy.
| Trivial name | RWJ 64809, PB 203580 |
| Catalog Number | S1076 |
| Molecular Formula | C5H10O |
| CAS# | 152121-47-6 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CC(C)CC=O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/SB-203580.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB-203580-chemical-structure-S1076.gif |
