Oxamflatin
A potent inhibitor of mammalian histone deacetylases (HDACs) (IC50 = 15.7 nM). A novel antitumor agent; oxamflatin modifies epigenetic status and gene expression, increases blastocyst quality, and subsequently enhances the nuclear reprogramming and developmental potential of SCNT (somatic cell nuclear transfer) embryos.
| Catalog Number | ABH-015 |
| Alternative Name(s) | N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-2E-penten-4-ynamide; Metacept 3 |
| CAS# | 151720-43-3 |
| Inchi | InChI=1S/C17H14N2O4S/c20-17(18-21)12-5-4-7-14-8-6-9-15(13-14)19-24(22,23)16-10-2-1-3-11-16/h1-3,5-6,8-13,19,21H,(H,18,20)/b12-5+ |
| Inchi Key | QRPSQQUYPMFERG-LFYBBSHMSA-N |
| SMILES | C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C#CC=CC(=O)NO |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/oxamflatin-item-1430.html |