BC-1215
BC-1215 is an inhibitor of F-box protein 3 (Fbxo3, a ubiquitin E3 ligase component) with IC50 of 0.9 μg/mL and LC50 of 87 μg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.
| Trivial name | N/A |
| Catalog Number | S0322 |
| Molecular Formula | C26H26N4 |
| CAS# | 1507370-20-8 |
| SMILES | C1=CC=NC(=C1)C2=CC=C(C=C2)CNCCNCC3=CC=C(C=C3)C4=CC=CC=N4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/bc-1215.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0322-bc-1215-chemical-structure.gif |