Asciminib (ABL001)
Asciminib (ABL001) is a potent and selective allosteric ABL1 inhibitor with dissociation constant (Kd) of 0.5-0.8 nM and selectivity to the myristoyl pocket of ABL1.
Trivial name | N/A |
Catalog Number | S8555 |
Molecular Formula | C20H18ClF2N5O3 |
CAS# | 1492952-76-7 |
Inchi | InChI=1S/C20H18ClF2N5O3/c21-20(22,23)31-15-3-1-13(2-4-15)26-19(30)12-9-16(17-5-7-25-27-17)18(24-10-12)28-8-6-14(29)11-28/h1-5,7,9-10,14,29H,6,8,11H2,(H,25,27)(H,26,30)/t14-/m1/s1 |
Inchi Key | VOVZXURTCKPRDQ-CQSZACIVSA-N |
SMILES | C1CN(CC1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=CC=NN4 |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/asciminib-abl001.html |
Additional Information | https://file.selleck.cn/downloads/struct/asciminib-abl001-chemical-structure-s8555.gif |