(Z)-RG-13022 | MedChemExpress (MCE)
(Z)-RG-13022 is a tyrosine kinase (TK) inhibitor, which inhibits preferentially the TK activity of the EGF receptor and inhibits EGF-stimulated growth of cultured cells. (Z)-RG-13022 exerts an IC50 of 11 μM for DNA synthesis in the HN5 cells, which is 3 times more potent than (E)-RG-13022 (IC50=38 μM). (Z)-RG-13022 can be used for research of breast cancer cells[1][2].
| Trivial name | (Z)-RG-13022 |
| Catalog Number | HY-117523 |
| Alternative Name(s) | (Z)-Tyrphostin RG13022 |
| Research Area | Cancer |
| CAS# | 149286-90-8 |
| Purity | ≥98.0% |
| SMILES | N#C/C(C1=CN=CC=C1)=C\C2=CC(OC)=C(C=C2)OC |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/z-rg-13022.html |