CCT245737 (SRA737)
CCT245737 (SRA737) is an orally active CHK1 inhibitor with The IC50 of 1.4 nM. It exhibits >1,000-fold selectivity against CHK2 and CDK1.
| Trivial name | PNT-737 |
| Catalog Number | S8253 |
| Molecular Formula | C16H16F3N7O |
| CAS# | 1489389-18-5 |
| Inchi | InChI=1S/C16H16F3N7O/c17-16(18,19)12-8-25-14(26-15-9-22-10(4-20)5-24-15)3-13(12)23-7-11-6-21-1-2-27-11/h3,5,8-9,11,21H,1-2,6-7H2,(H2,23,24,25,26)/t11-/m1/s1 |
| Inchi Key | YBYYWUUUGCNAHQ-LLVKDONJSA-N |
| SMILES | C1COC(CN1)CNC2=CC(=NC=C2C(F)(F)F)NC3=NC=C(N=C3)C#N |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/cct245737.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cct245737-chemical-structure-s8253.gif |