Tyrphostin AG 879
Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 μM, 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR.
| Trivial name | AG 879 |
| Catalog Number | S2816 |
| Molecular Formula | C23H21F3N6S |
| CAS# | 148741-30-4 |
| Inchi | InChI=1S/C23H21F3N6S/c24-23(25,26)10-18-9-19-21(28-13-29-22(19)33-18)31-16-3-5-32(6-4-16)12-14-1-2-20-15(7-14)8-17(11-27)30-20/h1-2,7-9,13,16,30H,3-6,10,12H2,(H,28,29,31) |
| Inchi Key | PSOJDGBGVBEYJX-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1NC2=C3C=C(SC3=NC=N2)CC(F)(F)F)CC4=CC5=C(C=C4)NC(=C5)C#N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tyrphostin-ag-879-ag-879.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AG-879-chemical-structure-s2816.gif |