VX-984

VX-984 is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSCLC) studies.

Price Not Available 25 mg VX-984 Supplier Page
Catalog Number T11067
Alternative Name(s) M9831
Research Area PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Molecular Formula C23H23N7O
CAS# 1476074-39-1
Purity 97.65%
SMILES [C@H](CNC=1C=C(N=CN1)C=2C(=NC(C)=NC2[2H])[2H])(C)C=3C4=C(C(C(NC)=O)=CC=N4)C=CC3
Size 25 mg
Supplier Page https://www.targetmol.com/compound/VX-984
Additional Information https://www.targetmol.com/datasheet/T11067