VX-984
VX-984 is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSCLC) studies.

Catalog Number | T11067 |
Alternative Name(s) | M9831 |
Research Area | PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair |
Molecular Formula | C23H23N7O |
CAS# | 1476074-39-1 |
Purity | 97.65% |
SMILES | [C@H](CNC=1C=C(N=CN1)C=2C(=NC(C)=NC2[2H])[2H])(C)C=3C4=C(C(C(NC)=O)=CC=N4)C=CC3 |
Size | 25 mg |
Supplier Page | https://www.targetmol.com/compound/VX-984 |
Additional Information | https://www.targetmol.com/datasheet/T11067 |