Hck-IN-1
Hck-IN-1, a selective Nef-dependent Hck inhibitor, blocks the kinase activity of the Nef:Hck complex in vitro with an IC50 value of 2.8 μM, whereas its activity against Hck alone is >20 μM, also blocks wild-type HIV-1 replication with an IC50 value in the 100-300 nM range.
| Catalog Number | E2834 |
| Molecular Formula | C16H11ClN6O3S |
| CAS# | 1473404-51-1 |
| SMILES | NC(=S)[N]1N=C(C2=CC=C(C=C2)[N;v5](=O)=O)C(=C1O)N=NC3=CC(=CC=C3)Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/hck-in-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e2834-hck-in-1-chemical-structure.gif |