Adavivint (SM04690)

Adavivint (SM04690,Lorecivivint) is a potent and specific inhibitor of canonical Wnt signaling with an EC50 of 19.5 nM for inhibiting the TCF/LEF reporter. It is ∼150- to 500-fold more potent than the other known Wnt inhibitors across multiple cellular assays.

Price Not Available 25mg Adavivint (SM04690) Supplier Page

Trivial name	Lorecivivint
Catalog Number	S8761
Molecular Formula	C29H24FN7O
CAS#	1467093-03-3
Inchi	InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28(37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
Inchi Key	AQDWDWAYVBQMAM-UHFFFAOYSA-N
SMILES	CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C(C=C2)NN=C3C4=NC5=C(N4)C=NC=C5C6=CC(=CC=C6)F
Size	25mg
Supplier Page	http://www.selleckchem.com/products/adavivint.html
Additional Information	https://file.selleck.cn/downloads/struct/adavivint-sm04690-chemical-structure-s8761.gif