PF-06409577
PF-06409577 is an orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.
| Trivial name | N/A |
| Catalog Number | S8335 |
| CAS# | 1467057-23-3 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/pf-06409577.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pf-06409577-chemical-structure-s8335.gif |