Tazemetostat hydrobromide

Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective, and orally available inhibitor of EZH2. It inhibits EZH2 with IC50 values of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat hydrobromide also inhibits EZH1 with an IC50 of 392 nM.

Price Not Available 25mg Tazemetostat hydrobromide Supplier Page

Trivial name	EPZ-6438 hydrobromide
Catalog Number	E4850
Molecular Formula	C28H39N7O3
CAS#	1467052-75-0
Inchi	InChI=1S/C28H39N7O3/c1-5-22-27(37)34(3)23-17-29-28(32-25(23)35(22)20-8-6-7-9-20)31-21-11-10-18(16-24(21)38-4)26(36)30-19-12-14-33(2)15-13-19/h10-11,16-17,19-20,22H,5-9,12-15H2,1-4H3,(H,30,36)(H,29,31, 32)/t22-/m1/s1
Inchi Key	XQVVPGYIWAGRNI-JOCHJYFZSA-N
SMILES	CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Size	25mg
Supplier Page	http://www.selleckchem.com/products/tazemetostat-hydrobromide.html
Additional Information	https://file.selleck.cn/downloads/struct/E4850-Tazemetostat-hydrobromide-chemical-structure.png