Tazemetostat hydrobromide

Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective, and orally available inhibitor of EZH2. It inhibits EZH2 with IC50 values of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat hydrobromide also inhibits EZH1 with an IC50 of 392 nM.

Price Not Available 1g Tazemetostat hydrobromide Supplier Page

Trivial name	EPZ-6438 hydrobromide
Catalog Number	E4850
Molecular Formula	C21H20N2O5
CAS#	1467052-75-0
Inchi	InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
Inchi Key	BHLXTPHDSZUFHR-UHFFFAOYSA-N
SMILES	CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N
Size	1g
Supplier Page	http://www.selleckchem.com/products/tazemetostat-hydrobromide.html
Additional Information	https://file.selleck.cn/downloads/struct/E4850-Tazemetostat-hydrobromide-chemical-structure.png