Tyrphostin AG 1296
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12.3 μM and 1.8 μM in Swiss 3T3 cells. Tyrphostin AG1296 induces dramatic apoptosis in A375R cells.
| Trivial name | AG 1296 |
| Catalog Number | S8024 |
| Molecular Formula | C16H14N2O2 |
| CAS# | 146535-11-7 |
| Inchi | InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3 |
| Inchi Key | QNOXYUNHIGOWNY-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)N=CC(=N2)C3=CC=CC=C3)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/tyrphostin-ag-1296-ag-1296.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AG-1296-chemical-structure-s8024.gif |