Lorlatinib (PF-6463922)

Lorlatinib (PF-6463922) is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. PF-06463922 induces apoptosis. Phase 1.

Price Not Available 5mg Lorlatinib (PF-6463922) Supplier Page

Trivial name	N/A
Catalog Number	S7536
Molecular Formula	C21H19FN6O2
CAS#	1454846-35-5
Inchi	InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/s1
Inchi Key	IIXWYSCJSQVBQM-LLVKDONJSA-N
SMILES	CC1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/pf-06463922.html
Additional Information	https://file.selleck.cn/downloads/struct/pf-06463922-chemical-structure-s7536.gif