LY3009120
LY03009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. LY03009120 induces autophagy. Phase 1.
| Trivial name | DP-4978 |
| Catalog Number | S7842 |
| Molecular Formula | C23H29FN6O |
| CAS# | 1454682-72-4 |
| Inchi | InChI=1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,28,30) |
| Inchi Key | HHCBMISMPSAZBF-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ly3009120.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ly3009120-chemical-structure-s7842.gif |