TC-E5002(KDM2/7-IN-1)
TC-E5002(KDM2/7-IN-1) is a selective inhibitor of histone demethylase KDM2/7 subfamily with IC50s of 6.8, 0.2, and 1.2 µM for KDM2A, KDM7A, and KDM7B, respectively. It is selective for the KDM2/7 subfamily over KDM4A, KDM4C, KDM5A, and KDM6A/UTX with IC50s of >120, 83, 55, and 100 µM, respectively. It exhibits antiproliferative activity, indicating its potential as an anticancer agent.
| Trivial name | KDM2/7-IN-1 |
| Catalog Number | E1793 |
| Molecular Formula | C3H8O3S |
| CAS# | 1453071-47-0 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/kdm2-7-in-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1793-TC-E5002-KDM2-7-IN-1-chemical-structure.png |