Tegaserod
Tegaserod is an orally active agonist of serotonin receptor 4 (5-HT4R) and also acts as an antagonist of 5-HT2B receptor with pKi values of 7.5, 8.4, and 7.0 for human recombinant 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. Tegaserod has anti-tumor activity and is used in the research of irritable bowel syndrome (IBS).
| Catalog Number | E4976 |
| Molecular Formula | C16H17N3O4S |
| CAS# | 145158-71-0 |
| Inchi | InChI=1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20) |
| Inchi Key | TXZPMHLMPKIUGK-UHFFFAOYSA-N |
| SMILES | CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/tegaserod.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4976-Tegaserod-chemical-structure.png |