SAR-20347
SAR-20347 is a potent inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediated IL-12 and IFN-α signaling.
| Trivial name | N/A |
| Catalog Number | S0437 |
| Molecular Formula | C21H18ClFN4O4 |
| CAS# | 1450881-55-6 |
| SMILES | C1COCCN1C(=O)C2=CC=C(C=C2)NC3=C(N=C(O3)C4=C(C=CC=C4Cl)F)C(=O)N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sar-20347.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0437-sar-20347-chemical-structure.gif |