CPI-169
CPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
| Trivial name | N/A |
| Catalog Number | S7616 |
| Molecular Formula | C27H36N4O5S |
| CAS# | 1450655-76-1 |
| Inchi | InChI=1S/C27H36N4O5S/c1-6-37(34,35)30-13-11-20(12-14-30)18(3)31-19(4)25(21-9-7-8-10-23(21)31)27(33)28-16-22-24(36-5)15-17(2)29-26(22)32/h7-10,15,18,20H,6,11-14,16H2,1-5H3,(H,28,33)(H,29,32)/t18-/m1/s1 |
| Inchi Key | LHGUZCKPFXXVPV-GOSISDBHSA-N |
| SMILES | CCS(=O)(=O)N1CCC(CC1)C(C)N2C(=C(C3=CC=CC=C32)C(=O)NCC4=C(C=C(NC4=O)C)OC)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/cpi-169.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cpi-169-chemical-structure-s7616.gif |