Siremadlin (HDM201)

Siremadlin (HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.

Price Not Available 10mM/1mL Siremadlin (HDM201) Supplier Page

Trivial name	NVP-HDM201
Catalog Number	S8606
Molecular Formula	C26H24Cl2N6O4
CAS#	1448867-41-1
Inchi	InChI=1S/C26H24Cl2N6O4/c1-13(2)33-21-19(30-22(33)17-11-29-26(38-5)31-23(17)37-4)25(36)34(18-10-16(28)12-32(3)24(18)35)20(21)14-6-8-15(27)9-7-14/h6-13,20H,1-5H3/t20-/m0/s1
Inchi Key	AGBSXNCBIWWLHD-FQEVSTJZSA-N
SMILES	CC(C)N1C2=C(C(=O)N(C2C3=CC=C(C=C3)Cl)C4=CC(=CN(C4=O)C)Cl)N=C1C5=CN=C(N=C5OC)OC
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/hdm201.html
Additional Information	https://file.selleck.cn/downloads/struct/hdm201-chemical-structure-s8606.gif